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DSM-IV: Substance Intoxication Delirium


Medications and other drugs including alcohol as well as other chemical toxins can cause Delirium associated with Intoxication. There must be evidence that the substance is present in the body and that the delirium has arisen from it.

Diagnostic criteria for Substance Intoxication Delirium  (cautionary statement)  

A. Disturbance of consciousness (i.e., reduced clarity of awareness of the environment) with reduced ability to focus, sustain, or shift attention. 

B. A change in cognition (such as memory deficit, disorientation, language disturbance) or the development of a perceptual disturbance that is not better accounted for by a preexisting, established, or evolving dementia

C. The disturbance develops over a short period of time (usually hours to days) and tends to fluctuate during the course of the day. 

D. There is evidence from the history, physical examination, or laboratory findings of either (1) or (2):

(1) the symptoms in Criteria A and B developed during Substance Intoxication 
(2) medication use is etiologically related to the disturbance* 

Note: This diagnosis should be made instead of a diagnosis of Substance Intoxication only when the cognitive symptoms are in excess of those usually associated with the intoxication syndrome and when the symptoms are sufficiently severe to warrant independent clinical attention. 

*Note: The diagnosis should be recorded as Substance-Induced Delirium if related to medication use. Refer to Appendix G for E-codes indicating specific medications. 

Code [Specific Substance] Intoxication Delirium: 

(291.0 Alcohol; 292.81 Amphetamine [or Amphetamine-Like Substance]; 292.81 Cannabis; 292.81 Cocaine; 292.81 Hallucinogen; 292.81 Inhalant; 292.81 Opioid; 292.81 Phencyclidine [or Phencyclidine-Like Substance]; 292.81 Sedative, Hypnotic, or Anxiolytic; 292.81 Other [or Unknown] Substance [e.g., cimetidine, digitalis, benztropine])

Reprinted with permission from the Diagnostic and Statistical Manual of Mental Disorders, fourth Edition. Copyright 1994 American Psychiatric Association

Associated with these drugs: alcohol, amphetamine, cannabis, cocaine, hallucinogens, inhalants, opioids, phencyclidine, sedatives, hypnotics

Also: substance induced delirium



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