A state in which an increased dosage of psychoactive substance
is needed
to produce a desired effect.*
Also: tachyphylaxis
Books and Other
Media:
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Frankenstein
Colin Clive, Mae Clarke, Boris Karloff, and John Boles 1931 -

Igby Goes Down
Kieran Culkin, Susan Sarandon, Jeff Goldblum, and Claire Danes 2002
*Excerpt with permission from Graham, Allan W. & Schultz, Terry K.
(Editors)
Principles of Addiction Medicine, 2nd Edition
Hardcover 1998 (American Society of Addiction Medicine)
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