drug: mirtazapine
U.S. Preparations:
Preparations Outside U.S.:
- Norset, Promyrtil, Remergil, Rexer, Zispin
Stephen Stahl's Clinical Pearls* (Consult your physician before making any change in
your treatment.)
- Sedation may be INVERSELY related to dose.
- Lowering dose may thus increase sedation.
- Two mechanisms (NE plus 5-HT) may be better than one (5HT alone)
for severe or refractory depression.
- Consider for panic disorder.
- Consider for mixed anxiety depression.
- Low likelihood of drug interactions
(except MAOI)
- Adding alpha-2 antagonism to agents
which act as reuptake blockers may be useful for refractory depression.
- Adding mirtazapine's 5-HT2 antagonism may reduce SSRI-
or venlafaxine-induced anxiety or insomnia.
- Adding mirtazapine's 5-HT3 antagonism may reduce SSRI- or venlafaxine-induced
nausea.
Books and Other
Media:
Follow the hypertext link to purchase items. |
 |
*Reprinted with permission from: Stahl, Stephen M Psychopharmacology
of Antidepressants Paperback 1997 Martin Dunitz, Ltd
& Blackwell Science You cannot
fully appreciate this book until you have seen the extraordinary illustrations
of every aspect of this area of psychopharmacology and neurochemistry. Loaded
with practical clinical "pearls."
|
