Single Episode Major Depressive Disorder

A. Presence of a single Major Depressive Episode. 

B. The Major Depressive Episode is not better accounted for by Schizoaffective Disorder and is not superimposed on Schizophrenia, Schizophreniform Disorder, Delusional Disorder, or Psychotic Disorder Not Otherwise Specified. 

C. There has never been a Manic Episode, a Mixed Episode, or a Hypomanic Episode. Note: This exclusion does not apply if all of the manic-like, mixed-like, or hypomanic-like episodes are substance or treatment induced or are due to the direct physiological effects of a general medical condition. 

Specify (for current or most recent episode): 

Severity/Psychotic/Remission Specifiers 
Chronic 
With Catatonic Features 
With Melancholic Features
With Atypical Features 
With Postpartum Onset 

Reprinted with permission from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Copyright 2000 American Psychiatric Association