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general paresis of the insane
( dementia paralytica, general paralysis, polyparesis, paralytic dementia )
Before Salvarsan (an arsenic compound) and penicillin were developed as effective treatments this late manifestation of tertiary cerebral neurosyphilis accounted for a substantial proportion of the residents in mental hospitals. Now rare, it is classified as a Mental Disorder Due to a General Medical Condition whose manifestations include Dementia and other symptoms.