The National Institute of Mental Health Research Domain Criteria (RDoC)
In draft research domain criteria, a Construct of a Negative Valence System
"Activation of a brain system in which harm may potentially occur but is distant, ambiguous, or low/uncertain in probability, characterized by a pattern of responses such as enhanced risk assessment (vigilance). These responses to low imminence threats are qualitatively different than the high imminence threat behaviors that characterize fear."
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